Key features and details
- Rabbit polyclonal to ID2
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-ID2 antibody
See all ID2 primary antibodies
DescriptionRabbit polyclonal to ID2
SpecificityDue to the similarity of this protein with ID1, ab217551 has a chance to have light cross-reactivity with ID1 due to a 77% sequence similarity in the range of our immunogen.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Rat
Predicted to work with: Mouse, Human
Synthetic peptide within Human ID2 aa 33-82 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: Q02363
- Rat brain tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab217551 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
FunctionID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
Tissue specificityHighly expressed in early fetal tissues, including those of the central nervous system.
Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
Developmental stageFound in most early fetal tissues but not in the corresponding mature tissues.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- bHLHb26 antibody
- Cell growth inhibiting gene 8 antibody
- class B basic helix loop helix protein 26 antibody
ab217551 has been referenced in 1 publication.
- Liu T et al. miR-27a promotes endothelial-mesenchymal transition in hypoxia-induced pulmonary arterial hypertension by suppressing BMP signaling. Life Sci 227:64-73 (2019). PubMed: 31004656