Overview

  • Product name

    Anti-IDH3B antibody - N-terminal
    See all IDH3B primary antibodies
  • Description

    Rabbit polyclonal to IDH3B - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to N terminal amino acids 86-135 (SEVQNMASEE KLEQVLSSMK ENKVAIIGKI HTPMEYKGEL ASYDMRLRRK) of Human IDH3B (NP_008830)

  • Positive control

    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab135444 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • Involvement in disease

    Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similarities

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ11043 antibody
    • H-IDHB antibody
    • Idh3B antibody
    • IDH3B_HUMAN antibody
    • Isocitrate dehydrogenase [NAD] subunit beta antibody
    • Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial antibody
    • isocitrate dehydrogenase 3, beta subunit antibody
    • Isocitric dehydrogenase antibody
    • Isocitric dehydrogenase subunit beta antibody
    • MGC903 antibody
    • mitochondrial antibody
    • NAD(+)-specific ICDH antibody
    • NAD(+)-specific ICDH subunit beta antibody
    • NAD+-specific isocitrate dehydrogenase b subunit antibody
    • NAD+-specific isocitrate dehydrogenase beta antibody
    • OTTHUMP00000030023 antibody
    • OTTHUMP00000030024 antibody
    • RP46 antibody
    see all

Images

  • Anti-IDH3B antibody - N-terminal (ab135444) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size: 42 kDa

References

ab135444 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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