Anti-IDO-2 antibody - C-terminal (ab170614)

Overview

  • Product name
    Anti-IDO-2 antibody - C-terminal
    See all IDO-2 primary antibodies
  • Description
    Rabbit polyclonal to IDO-2 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IDO-2 aa 274-303 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q6ZQW0

  • Positive control
    • K562 cell line lysates and Human liver tissue.
  • General notes

    Protein previously labeled as INDOL1.

Properties

Applications

Our Abpromise guarantee covers the use of ab170614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism.
  • Tissue specificity
    Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon.
  • Pathway
    Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
  • Sequence similarities
    Belongs to the indoleamine 2,3-dioxygenase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-dioxygenase 2 antibody
    • 3-dioxygenase-like protein 1 antibody
    • EC 1.13.11. antibody
    • I23O2_HUMAN antibody
    • IDO 2 antibody
    • IDO-2 antibody
    • Ido2 antibody
    • INDOL 1 antibody
    • Indoleamine 2 antibody
    • Indoleamine 2,3 dioxygenase 2 antibody
    • Indoleamine 2,3 dioxygenase like 1 protein antibody
    • Indoleamine 2,3 dioxygenase like protein 1 antibody
    • Indoleamine pyrrole 2,3 dioxygenase like 1 antibody
    • Indoleamine pyrrole 2,3 dioxygenase like protein 1 antibody
    • Indoleamine-pyrrole 2 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human liver tissue labeling IDO-2 with ab170614 antibody at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-IDO-2 antibody - C-terminal (ab170614) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size: 45 kDa

References

ab170614 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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