Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Constituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab171919 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 11 kDa.|
FunctionPromotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
Sequence similaritiesBelongs to the IFI6/IFI27 family.
Cellular localizationMitochondrion. Membrane.
- Information by UniProt
- 2310061N23Rik antibody
- FAM 14D antibody
- FAM14D antibody
This product has been referenced in:
- Liu Z et al. miR-370 regulates ISG15 expression and influences IFN-a sensitivity in hepatocellular carcinoma cells. Cancer Biomark 22:453-466 (2018). Read more (PubMed: 29758929) »
- Liu N et al. miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT. Oncotarget 5:4959-71 (2014). Read more (PubMed: 24970806) »