Key features and details
- Rabbit polyclonal to IFITM1
- Suitable for: WB, IHC-P, IHC-Fr
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IFITM1 antibody
See all IFITM1 primary antibodies
DescriptionRabbit polyclonal to IFITM1
Tested applicationsSuitable for: WB, IHC-P, IHC-Frmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to a sequence at the N terminus of Human IFITM1, identical to the related Rat and Mouse sequence.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106265 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 14 kDa.|
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Boiling the sections is required.|
|IHC-Fr||Use at an assay dependent concentration.|
FunctionIFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
Sequence similaritiesBelongs to the CD225 family.
modificationsPalmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus.
Cellular localizationCell membrane.
- Information by UniProt
- 9-27 antibody
- CD 225 antibody
- CD 225 antigen antibody
ab106265 has been referenced in 1 publication.
- Everitt AR et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature : (2012). IHC-G ; Mouse . PubMed: 22446628