Overview

  • Product name

    Anti-IgA1 antibody [B3506B4]
    See all IgA1 primary antibodies
  • Description

    Mouse monoclonal [B3506B4] to IgA1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ELISA, IHC-Frmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Immunogen information is proprietary

Properties

Applications

Our Abpromise guarantee covers the use of ab128791 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 38 kDa.
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • Relevance

    Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • Ig alpha 1 chain C region antibody
    • IGHA1 antibody
    • immunoglobulin heavy constant alpha 1 antibody

References

This product has been referenced in:

  • Lu G  et al. CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy. PLoS One 12:e0178352 (2017). Read more (PubMed: 28552941) »
See 1 Publication for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Human Tissue sections (Tonsil)
Antigen retrieval step
Heat mediated
Permeabilization
No
Specification
Tonsil
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative
Formaldehyde

Abcam user community

Verified customer

Submitted Aug 24 2018

Answer

Thank you for contacting us.

In general, the selection of the immunogen varies from antibody to antibody. Some antibodies are raised against synthetic peptides (based ona protein sequence which was derived originally from a DNA sequence), some against protein fragments and others against the full length protein (either purified or overexpressed in another organism) or a cell preparation.

Which specific antibody or protein target do you have in mind?

As for the anti-IgA antibodies - the immunogendepends on the antibody.

Please let me know more details about the products of your interest and I'd be happy to assist you further.

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