Recombinant
RabMAb

Anti-IGBP1 antibody [EPR12315] (ab170911)

Overview

  • Product name
    Anti-IGBP1 antibody [EPR12315]
    See all IGBP1 primary antibodies
  • Description
    Rabbit monoclonal [EPR12315] to IGBP1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IF, Flow Cyt, IHC-Pmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human IGBP1 aa 50-150 (Cysteine residue). The exact sequence is proprietary.
    Database link: P78318

  • Positive control
    • K562, Jurkat, HeLa and Raji cell lysates; Human pancreas tissue; Human tonsil tissue; K562 cells; HeLa cells
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR12315
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170911 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 39 kDa.
ICC/IF 1/100 - 1/250.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

IHC-P 1/100 - 1/250.

Antigen retrieval is recommended.

  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Associated to surface IgM-receptor; may be involved in signal transduction. May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases.
    • Tissue specificity
      Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas.
    • Involvement in disease
      Defects in IGBP1 are the cause of agenesis of the corpus callosum with mental retardation-ocular coloboma-micrognathia (ACCMRCM) [MIM:300472].
    • Sequence similarities
      Belongs to the IGBP1/TAP42 family.
    • Post-translational
      modifications
      Phosphorylated.
    • Cellular localization
      Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alpha 4 antibody
      • B cell signal transduction molecule alpha 4 antibody
      • B-cell signal transduction molecule alpha 4 antibody
      • bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ) antibody
      • bA351K23.1 antibody
      • CD79a binding protein 1 antibody
      • CD79a-binding protein 1 antibody
      • IBP 1 antibody
      • IBP1 antibody
      • IGBP 1 antibody
      • Igbp1 antibody
      • IGBP1_HUMAN antibody
      • Immunoglobulin (CD79A) binding protein 1 antibody
      • Immunoglobulin binding protein 1 antibody
      • Immunoglobulin-binding protein 1 antibody
      • Protein alpha 4 antibody
      • Protein alpha-4 antibody
      • Protein phosphatase 2/4/6 regulatory subunit antibody
      • Protein phosphatase 2A regulatory subunit alpha 4 antibody
      • Renal carcinoma antigen NY REN 16 antibody
      • Renal carcinoma antigen NY-REN-16 antibody
      see all

    Images

    • Immunofluorescent staining of HeLa cells labeling IGBP1 using ab170911 at 1/100 dilution (red). DAPI nuclear staining (blue).

    • All lanes : Anti-IGBP1 antibody [EPR12315] (ab170911) at 1/1000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : Raji cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 39 kDa

    • Flow cytometric analysis of permeabilized K562 cells labeling IGBP1 using ab170911 at 1/100 dilution (red) or a rabbit IgG negative (green).

    • Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling IGBP1 using ab170911 at 1/100 dilution.

    • Immunohistochemical analysis of paraffin- embedded Human pancreas tissue labeling IGBP1 using  ab170911 at 1/100 dilution.

    References

    ab170911 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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