Key features and details
- Rabbit polyclonal to IgE, prediluted
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IgE antibody, prediluted
See all IgE primary antibodies
DescriptionRabbit polyclonal to IgE, prediluted
SpecificityThis antibody recognizes IgE, epsilon heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), mu (IgM), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Full length IgE isolated from a pool of normal human sera.
- Human Tonsil tissue
This antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.60
Preservative: 0.0975% Sodium azide
Constituent: 0.79% Tris HCl
Containing antibody stabilizer
Concentration information loading...
PurityProtein A purified
Primary antibody notesThis antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas.
Our Abpromise guarantee covers the use of ab75673 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Ready to use.
RelevanceIgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
Cellular localizationCell Membrane
- Igh2 antibody
- IGHE antibody
- IGHEP1 antibody
- Immunoglobulin heavy constant epsilon antibody
ab75673 has been referenced in 2 publications.
- Ningyan G et al. The role of macrophage migration inhibitory factor in mast cell-stimulated fibroblast proliferation and collagen production. PLoS One 10:e0122482 (2015). PubMed: 25826375
- Motegi S et al. Elevated serum levels of TARC/CCL17, Eotaxin-3/CCL26 and VEGF in a patient with Kimura's disease and prurigo-like eruption. Acta Derm Venereol 94:112-3 (2014). PubMed: 23756566