Anti-IGF1 Receptor (phospho Y1161) antibody (ab39398)

Rabbit polyclonal IGF1 Receptor (phospho Y1161) antibody. Validated in WB, IP, ELISA, IHC, ICC, ICC/IF and tested in Mouse, Rat, Human. Cited in 34 publication(s). Independently reviewed in 17 review(s).

Publishing research using ab39398? Please let us know so that we can cite the reference in this datasheet.

ab39398 has been referenced in 37 publications.

  • Wang SQ  et al. Knockdown of IGF-1R Triggers Viral RNA Sensor MDA5- and RIG-I-Mediated Mitochondrial Apoptosis in Colonic Cancer Cells. Mol Ther Nucleic Acids 16:105-117 (2019). PubMed: 30861413
  • Gao JX  et al. Overexpression of microRNA-183 promotes apoptosis of substantia nigra neurons via the inhibition of OSMR in a mouse model of Parkinson's disease. Int J Mol Med 43:209-220 (2019). PubMed: 30431059
  • Jiang W  et al. Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer. Oncol Lett 16:6445-6457 (2018). PubMed: 30405782
  • Zhang C  et al. MicroRNA-302a inhibits osteosarcoma cell migration and invasion by directly targeting IGF-1R. Oncol Lett 15:5577-5583 (2018). PubMed: 29563995
  • Wu H  et al. Whole Body Vibration Retards Progression of Atherosclerosis via Insulin-Like Growth Factor 1 in Apolipoprotein E-Deficient Mice. Biomed Res Int 2018:4934861 (2018). PubMed: 29707570
  • Youssif C  et al. Myeloid p38a signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis. EMBO Mol Med 10:N/A (2018). PubMed: 29907597
  • Sun L  et al. Impact of Estrogen on the Relationship Between Obesity and Renal Cell Carcinoma Risk in Women. EBioMedicine 34:108-112 (2018). PubMed: 30017803
  • Shi-Peng G  et al. TMED2 promotes epithelial ovarian cancer growth. Oncotarget 8:94151-94165 (2017). PubMed: 29212217
  • Ochnik AM & Baxter RC Insulin-like growth factor receptor and sphingosine kinase are prognostic and therapeutic targets in breast cancer. BMC Cancer 17:820 (2017). PubMed: 29207959
  • Shi W  et al. TrkA is a binding partner of NPM-ALK that promotes the survival of ALK+ T-cell lymphoma. Mol Oncol 11:1189-1207 (2017). IHC . PubMed: 28557340
  • Zhao Z  et al. Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. Front Mol Neurosci 10:293 (2017). PubMed: 28959186
  • Liu Z  et al. Detection of microRNA-200b may predict the inhibitory effect of gefitinib on non-small cell lung cancer and its potential mechanism. Oncol Lett 12:5349-5355 (2016). PubMed: 28101246
  • Mitchell J  et al. Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs. Oncology 91:90-100 (2016). PubMed: 27305144
  • Kero D  et al. Involvement of IGF-2, IGF-1R, IGF-2R and PTEN in development of human tooth germ - an immunohistochemical study. Organogenesis 12:152-167 (2016). PubMed: 27326759
  • Dimitrova N  et al. Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov 6:188-201 (2016). PubMed: 26586766
  • Huang M  et al. Anti-proliferative role and prognostic implication of miR-141 in gastric cancer. Am J Transl Res 8:3549-57 (2016). WB ; Mouse . PubMed: 27648145
  • Ding WZ  et al. MicroRNA-497 regulates cell proliferation in hepatocellular carcinoma. Oncol Lett 11:1081-1088 (2016). WB, IHC-P ; Human . PubMed: 26893696
  • Allodi I  et al. Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS. Sci Rep 6:25960 (2016). PubMed: 27180807
  • Wang HF  et al. Effects of lactic acid bacteria on cardiac apoptosis are mediated by activation of the phosphatidylinositol-3 kinase/AKT survival-signalling pathway in rats fed a high-fat diet. Int J Mol Med 35:460-70 (2015). PubMed: 25484003
  • Chung SH  et al. Profiling of microRNAs involved in retinal degeneration caused by selective Müller cell ablation. PLoS One 10:e0118949 (2015). WB ; Mouse . PubMed: 25741709
  • Park JH  et al. Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer. Neoplasia 17:421-33 (2015). IHC-P ; Mouse . PubMed: 26025665
  • Wang T  et al. Osteoblast-Specific Loss of IGF1R Signaling Results in Impaired Endochondral Bone Formation During Fracture Healing. J Bone Miner Res 30:1572-84 (2015). PubMed: 25801198
  • Croner RS  et al. Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis. Int J Cancer 135:2878-86 (2014). PubMed: 24771638
  • George SK  et al. The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget 5:5750-63 (2014). PubMed: 25026277
  • Liang Z  et al. Insulin-like growth factor 1 receptor is a prognostic factor in classical Hodgkin lymphoma. PLoS One 9:e87474 (2014). IHC-P ; Human . PubMed: 24489919
  • Pan T  et al. Cytohesins/ARNO: the function in colorectal cancer cells. PLoS One 9:e90997 (2014). WB ; Human . PubMed: 24618737
  • Corrochano S  et al. Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice. PLoS One 9:e105595 (2014). WB ; Mouse . PubMed: 25140802
  • Lovly CM  et al. Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer. Nat Med 20:1027-34 (2014). PubMed: 25173427
  • Hu ZC  et al. Expression of insulin-like growth factor-1 receptor in keloid and hypertrophic scar. Clin Exp Dermatol 39:822-8 (2014). IHC ; Human . PubMed: 25154292
  • Hahn AM  et al. Interleukin-driven insulin-like growth factor promotes prostatic inflammatory hyperplasia. J Pharmacol Exp Ther 351:605-15 (2014). PubMed: 25292180
  • Nguyen DH  et al. Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice. Cancer Res 74:7149-58 (2014). PubMed: 25281718
  • Lai LP  et al. Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A 110:19450-5 (2013). PubMed: 24218567
  • Bedzhov I  et al. Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. PLoS Genet 8:e1002609 (2012). ICC/IF ; Mouse . PubMed: 22479204
  • Litzenburger BC  et al. High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res 17:2314-27 (2011). IHC-P ; Human . PubMed: 21177763
  • Honda T  et al. Upregulation of insulin-like growth factor binding protein 3 in astrocytes of transgenic mice that express Borna disease virus phosphoprotein. J Virol 85:4567-71 (2011). WB . PubMed: 21325425
  • Bitoun E  et al. AF4 is a critical regulator of the IGF-1 signaling pathway during Purkinje cell development. J Neurosci 29:15366-74 (2009). IHC-P ; Mouse . PubMed: 20007461
  • Gatchel JR  et al. The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7. Proc Natl Acad Sci U S A 105:1291-6 (2008). WB, IHC-FoFr ; Mouse . PubMed: 18216249

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