Anti-IGFBP1 antibody (ab231259)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-IGFBP1 antibody
See all IGFBP1 primary antibodies -
Description
Rabbit polyclonal to IGFBP1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Pig -
Immunogen
Recombinant fragment (His-T7-tag) corresponding to Pig IGFBP1 aa 112-262. Expressed in E.coli. N-terminal tags.
Sequence:EATETKDPAAPETTSPESTEMTQEQLLDSFHLMATSSEDLPILWNAINNY ESMKALEATDIKKWKEPCQRELYKVLDRLAREQQKAGDRLYKFYLPNCNK NGFYHSKQCETSLEGEPGLCWCVYPWSGKKILGSTAVRGDPKCHQYFNSQ N
Database link: Q75ZP3 -
Positive control
- WB: Recombinant pig IGFBP1 protein; Pig liver, kidney and human placenta lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab231259 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | Use a concentration of 0.5 - 2 µg/ml. |
Target
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Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. -
Sequence similarities
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain. -
Post-translational
modificationsPhosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 397270 Pig
- SwissProt: Q75ZP3 Pig
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Alternative names
- AFBP antibody
- Alpha pregnancy associated endometrial globulin antibody
- Amniotic fluid binding protein antibody
see all
Images
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Anti-IGFBP1 antibody (ab231259) at 2 µg/ml + Pig liver lysate
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Anti-IGFBP1 antibody (ab231259) at 2 µg/ml + Pig kidney lysate
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Anti-IGFBP1 antibody (ab231259) at 2 µg/ml + Human placenta tissue lysate
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Anti-IGFBP1 antibody (ab231259) at 2 µg/ml + Recombinant pig IGFBP1 protein
Datasheets and documents
References
ab231259 has not yet been referenced specifically in any publications.