Overview

  • Product name

    Anti-IGFBP1 antibody [EPR14471(B)]
    See all IGFBP1 primary antibodies
  • Description

    Rabbit monoclonal [EPR14471(B)] to IGFBP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IGFBP1 aa 50-150. The exact sequence is proprietary.
    Database link: P08833

  • Positive control

    • HepG2 cell lysate; Human placenta and fetal liver lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab180948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).

Target

  • Function

    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
  • Sequence similarities

    Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • Post-translational
    modifications

    Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AFBP antibody
    • Alpha pregnancy associated endometrial globulin antibody
    • Amniotic fluid binding protein antibody
    • Binding protein 25 antibody
    • Binding protein 26 antibody
    • Binding protein 28 antibody
    • Growth hormone independent binding protein antibody
    • hIGFBP 1 antibody
    • hIGFBP1 antibody
    • IBP 1 antibody
    • IBP-1 antibody
    • IBP1 antibody
    • IBP1_HUMAN antibody
    • IGF binding protein 1 antibody
    • IGF BP25 antibody
    • IGF-binding protein 1 antibody
    • IGFBP 1 antibody
    • IGFBP-1 antibody
    • IGFBP1 antibody
    • Insulin like growth factor binding protein 1 antibody
    • Insulin-like growth factor-binding protein 1 antibody
    • Placental protein 12 antibody
    • PP 12 antibody
    • PP12 antibody
    see all

Images

  • All lanes : Anti-IGFBP1 antibody [EPR14471(B)] (ab180948) at 1/5000 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : Human placenta lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    All lanes : Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 28 kDa
    Observed band size: 28 kDa

  • Anti-IGFBP1 antibody [EPR14471(B)] (ab180948) at 1/20000 dilution + HepG2 cell lysate at 20 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 28 kDa
    Observed band size: 28 kDa

References

ab180948 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab180948.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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