Product nameIGFBP3 peptide
See all IGFBP3 proteins and peptides
Our Abpromise guarantee covers the use of ab156648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-IGFBP3 antibody (ab77635)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
ReconstitutionDissolve the peptide in distilled water and then top it up with the appropriate buffer.
- Acid stable subunit of the 140 K IGF complex
- Binding protein 29
- Binding protein 53
FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Tissue specificityExpressed by most tissues. Present in plasma.
Sequence similaritiesContains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.
Developmental stageIGFBP3 levels are higher during extrauterine life and peak during puberty.
DomainThe thyroglobulin type-1 domain mediates interaction with HN.
modificationsPhosphorylation sites are present in the extracelllular medium.
- Information by UniProt
ab156648 has not yet been referenced specifically in any publications.