Key features and details
- Rabbit polyclonal to IGFBP4
- Suitable for: IP, WB
- Reacts with: Mouse, Cow, Human, Pig
- Isotype: IgG
Product nameAnti-IGFBP4 antibody
See all IGFBP4 primary antibodies
DescriptionRabbit polyclonal to IGFBP4
Tested applicationsSuitable for: IP, WBmore details
Species reactivityReacts with: Mouse, Cow, Human, Pig
HPLC purified IGFBP 4 isolated from conditioned medium from the human glioblastoma cell line, T98G.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Concentration information loading...
Our Abpromise guarantee covers the use of ab4253 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000. Detects 1ng SDS-denatured human IGFBP 4 in concentrated serum free T98G culture supernatant. Predicted molecular weight: 24 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionIGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Sequence similaritiesContains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.
- Information by UniProt
- AI875747 antibody
- BP 4 antibody
- BP4 antibody
ab4253 has been referenced in 2 publications.
- Xiao Y et al. IGFBP-4 expression is adversely associated with lung cancer prognosis. Oncol Lett 14:6876-6880 (2017). PubMed: 29163706
- Pan H et al. Protein secretion is required for pregnancy-associated plasma protein-A to promote lung cancer growth in vivo. PLoS One 7:e48799 (2012). WB . PubMed: 23152806