Anti-IGFBP5 antibody (ab216622)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP5 antibody (ab216622)

    Key features and details

    • Rabbit polyclonal to IGFBP5
    • Suitable for: IHC-P
    • Reacts with: Rat, Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-IGFBP5 antibody
      See all IGFBP5 primary antibodies

    • Description

      Rabbit polyclonal to IGFBP5

    • Host species

      Rabbit

    • Tested applications

      Suitable for: IHC-Pmore details

    • Species reactivity

      Reacts with: Rat, Human
      Predicted to work with: Mouse

    • Immunogen

      Synthetic peptide within Human IGFBP5 aa 90-140 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
      Sequence:

      LHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRP K


      Database link: P24593
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • Positive control

      • Human nasopharyngeal carcinoma tissue.

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab216622 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P 1/100 - 1/500.

    Target

    • Function

      IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

    • Tissue specificity

      Osteosarcoma, and at lower levels in liver, kidney and brain.

    • Sequence similarities

      Contains 1 IGFBP N-terminal domain.
      Contains 1 thyroglobulin type-1 domain.

    • Cellular localization

      Secreted.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • IBP 5 antibody
      • IBP-5 antibody
      • IBP5 antibody
      • IBP5_HUMAN antibody
      • IGF binding protein 5 antibody
      • IGF BP5 antibody
      • IGF-binding protein 5 antibody
      • IGFBP 5 antibody
      • IGFBP-5 antibody
      • IGFBP5 antibody
      • Insulin like growth factor binding protein 5 antibody
      • Insulin-like growth factor-binding protein 5 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP5 antibody (ab216622)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP5 antibody (ab216622)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded human nasopharyngeal carcinoma tissue labeling IGFBP5 with ab216622 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

    References (0)

    Publishing research using ab216622? Please let us know so that we can cite the reference in this datasheet.

    ab216622 has not yet been referenced specifically in any publications.

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