Overview

  • Product name

    Anti-IgG4 antibody [IGHG4/1345]
    See all IgG4 primary antibodies
  • Description

    Mouse monoclonal [IGHG4/1345] to IgG4
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human IgG4. Molecular weight of immunogen: 150 kDa
    Database link: P01861

  • Positive control

    • IHC-P: Human tonsil tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: 99% PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    IGHG4/1345
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab218428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • Ig gamma 4 chain C region antibody
    • IGHG4 antibody
    • immunoglobulin heavy chain constant region gamma 4 antibody
    • Immunoglobulin heavy constant gamma 4 (G4m marker) antibody
    • MGC117419 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue, labeling IgG4 with ab218428 at 1 ug/mL.

References

ab218428 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab218428.
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