Validated using a knockout cell line

Recombinant Anti-IKK alpha antibody [Y463] (ab32041)

Publishing research using ab32041? Please let us know so that we can cite the reference in this datasheet.

ab32041 has been referenced in 22 publications.

  • Chen XL  et al. SENP2 exerts an anti-tumor effect on chronic lymphocytic leukemia cells through the inhibition of the Notch and NF-?B signaling pathways. Int J Oncol 54:455-466 (2019). PubMed: 30431078
  • Chen Y  et al. Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCe-NF-?B signaling pathway and VEGF-C/ Bcl-2 expression. Mol Cancer 18:1 (2019). PubMed: 30609930
  • Tang H  et al. miR-505 inhibits cell growth and EMT by targeting MAP3K3 through the AKT-NF?B pathway in NSCLC cells. Int J Mol Med 43:1203-1216 (2019). PubMed: 30628663
  • Jiang L  et al. Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-?B signaling. EBioMedicine 43:188-200 (2019). PubMed: 30979686
  • Yu J  et al. Three-gene immunohistochemical panel predicts progression and unfavorable prognosis in esophageal squamous cell carcinoma. Hum Pathol N/A:N/A (2018). PubMed: 30537494
  • Wang G  et al. Lycorine Suppresses Endplate-Chondrocyte Degeneration and Prevents Intervertebral Disc Degeneration by Inhibiting NF-?B Signalling Pathway. Cell Physiol Biochem 45:1252-1269 (2018). PubMed: 29448253
  • Zhang C  et al. Activation of TNF-a/NF-?B axis enhances CRL4BDCAF11E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells. Mol Oncol N/A:N/A (2018). WB . PubMed: 29377600
  • Li J  et al. Emodin attenuates titanium particle-induced osteolysis and RANKL-mediated osteoclastogenesis through the suppression of IKK phosphorylation. Mol Immunol 96:8-18 (2018). PubMed: 29455094
  • Zhang XY  et al. Anaphylatoxin C5a induces inflammation and reduces insulin sensitivity by activating TLR4/NF-kB/PI3K signaling pathway in 3T3-L1 adipocytes. Biomed Pharmacother 103:955-964 (2018). WB . PubMed: 29710512
  • Zhang Y  et al. HZ08 suppresses RelB-activated MnSOD expression and enhances Radiosensitivity of prostate Cancer cells. J Exp Clin Cancer Res 37:174 (2018). PubMed: 30053873
  • Zhang Y  et al. ETS1 is associated with cisplatin resistance through IKKa/NF-?B pathway in cell line MDA-MB-231. Cancer Cell Int 18:86 (2018). PubMed: 29950928
  • Zhang M  et al. The NF?B signaling pathway serves an important regulatory role in Klebsiella pneumoniae liver abscesses. Exp Ther Med 15:5443-5449 (2018). PubMed: 29904423
  • Zhang Y  et al. Uncoupling Protein 2 Inhibits Myointimal Hyperplasia in Preclinical Animal Models of Vascular Injury. J Am Heart Assoc 6:N/A (2017). PubMed: 29025747
  • Li X  et al. Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics 7:4671-4688 (2017). PubMed: 29187895
  • Cao L  et al. Clinical characteristics and molecular pathology of skull ectopic thyroid cancer. Ann Transl Med 4:462 (2016). PubMed: 28090518
  • Liu Z  et al. Mark4 promotes oxidative stress and inflammation via binding to PPAR? and activating NF-?B pathway in mice adipocytes. Sci Rep 6:21382 (2016). WB ; Mouse . PubMed: 26888669
  • Jung JU  et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol N/A:N/A (2016). Human . PubMed: 27889261
  • Li XJ  et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-?B signaling pathways in osteoprotegerin knockout mice. Int J Mol Med N/A:N/A (2016). WB ; Mouse . PubMed: 27840967
  • Benzina S  et al. Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways. J Cancer 7:2035-2044 (2016). PubMed: 28070224
  • Muñoz-Galván S  et al. MAP17 (PDZKIP1) Expression Determines Sensitivity to the Proteasomal Inhibitor Bortezomib by Preventing Cytoprotective Autophagy and NF?B Activation in Breast Cancer. Mol Cancer Ther 14:1454-65 (2015). PubMed: 25837675
  • Thorne JL  et al. Heterochromatin protein 1 gamma and I?B kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages. Nucleic Acids Res : (2012). IP ; Mouse . PubMed: 22649058
  • Wunderlich FT  et al. Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A 105:1297-302 (2008). PubMed: 18216263

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