Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-1 alpha
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Horse, Cow, Cat, Dog
    Does not react with: Rabbit, Dolphin
  • Immunogen

    Recombinant full length protein corresponding to Cow IL-1 alpha aa 120-268.
    Sequence:

    SNVKYNFMRV IHQECILNDA LNQSIIRDMS GPYLTATTLN NLEEAVKFDM VAYVSEEDSQ LPVTLRISKT QLFVSAQNED EPVLLKEMPE TPKIIKDETN LLFFWEKHGS MDYFKSVAHP KLFIATKQEK LVHMASGPPS ITDFQILEK


    Database link: P08831

  • General notes

    Cross-reactivity determined in ELISA.

Properties

Applications

Our Abpromise guarantee covers the use of ab193804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml. Predicted molecular weight: 31 kDa.

Target

  • Function

    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similarities

    Belongs to the IL-1 family.
  • Domain

    The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localization

    Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links

  • Alternative names

    • BAF antibody
    • FAF antibody
    • Hematopoietin 1 antibody
    • Hematopoietin-1 antibody
    • IL 1 alpha antibody
    • IL 1A antibody
    • IL-1 alpha antibody
    • Il-1a antibody
    • IL1 ALPHA antibody
    • IL1 antibody
    • IL1A antibody
    • IL1A_HUMAN antibody
    • IL1F1 antibody
    • Interleukin 1 alpha antibody
    • Interleukin-1 alpha antibody
    • Interleukin1 alpha antibody
    • LAF antibody
    • LEM antibody
    • Preinterleukin 1 alpha antibody
    • Pro interleukin 1 alpha antibody
    see all

References

ab193804 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab193804.
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