Overview

  • Product name

    Anti-IL-1 alpha antibody [C5]
    See all IL-1 alpha primary antibodies
  • Description

    Mouse monoclonal [C5] to IL-1 alpha
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat, Goat
    Predicted to work with: Sheep, Cow
  • Immunogen

    Recombinant fragment (His-tag) corresponding to Goat IL-1 alpha aa 90-268. N-terminal tag (Expressed in E.coli).
    Sequence:

    QFITDDDLEAIANDTEEEIIKPRSAHYSFQSNVKYNFMRVIHQECILNDA LNQSIIRDMSGPYLMAATLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKT QLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHP KLFIATKQEKLVHMASGPPSITDFQILEK


    Database link: P79161

  • Positive control

    • WB: Rat liver and lung lysates; goat liver and lung lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab239584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 5 µg/ml.

Target

  • Function

    Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similarities

    Belongs to the IL-1 family.
  • Domain

    The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localization

    Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
  • Information by UniProt
  • Database links

  • Alternative names

    • BAF antibody
    • FAF antibody
    • Hematopoietin 1 antibody
    • Hematopoietin-1 antibody
    • IL 1 alpha antibody
    • IL 1A antibody
    • IL-1 alpha antibody
    • Il-1a antibody
    • IL1 ALPHA antibody
    • IL1 antibody
    • IL1A antibody
    • IL1A_HUMAN antibody
    • IL1F1 antibody
    • Interleukin 1 alpha antibody
    • Interleukin-1 alpha antibody
    • Interleukin1 alpha antibody
    • LAF antibody
    • LEM antibody
    • Preinterleukin 1 alpha antibody
    • Pro interleukin 1 alpha antibody
    see all

Images

  • Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/ml + Rat liver lysate
  • Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/ml + Goat liver lysate
  • Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/ml + Goat lung lysate
  • Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/ml + Rat lung lysate

References

ab239584 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab239584.
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