Product nameAnti-IL-1 Receptor I / IL-1R-1 antibody [REG21]
See all IL-1 Receptor I / IL-1R-1 primary antibodies
DescriptionRat monoclonal [REG21] to IL-1 Receptor I / IL-1R-1
SpecificityBinds to soluble mouse interleukin-1 receptor type I. Interleukin-1 signal is transduced through the type I receptor.
Tested applicationsSuitable for: IP, Inhibition Assay, WB, Purificationmore details
Species reactivityReacts with: Mouse
Previously labelled as IL1 Receptor I.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab8154 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Inhib: Use at an assay dependent dilution.
P: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
ab8154 can be used for inhibition in biological assays (in vitro and in vivo).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
Sequence similaritiesBelongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
- Information by UniProt
- Antigen CD121a antibody
- CD121 antigen-like family member A antibody
- CD121a antibody