Overview

  • Product name
    Anti-IL-10RA antibody [1B1.3a]
    See all IL-10RA primary antibodies
  • Description
    Rat monoclonal [1B1.3a] to IL-10RA
  • Host species
    Rat
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
    Does not react with: Human
  • Immunogen

    Recombinant fragment corresponding to Mouse IL-10RA.

  • Epitope
    The epitope recognised by this antibody has been localised to the ligand binding domain within the extracellular region of mouse CD210 (IL-10RA).
  • General notes

     

    This clone is reported to neutralize the effects of IL-10.

Properties

Applications

Our Abpromise guarantee covers the use of ab33738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/100.

Use 10µl of the suggested working dilution to label 106 cells in 100µl.

 

 

 

ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Receptor for IL10; binds IL10 with a high affinity.
  • Tissue specificity
    Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
  • Involvement in disease
    Inflammatory bowel disease 28
  • Sequence similarities
    Belongs to the type II cytokine receptor family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD210 antibody
    • CDw210a antibody
    • CDw210a antigen antibody
    • HIL 10R antibody
    • HIL10R antibody
    • I10R1_HUMAN antibody
    • IL 10R 1 antibody
    • IL 10R A antibody
    • IL 10R antibody
    • IL 10R1 antibody
    • IL-10 receptor subunit alpha antibody
    • IL-10R subunit 1 antibody
    • IL-10R subunit alpha antibody
    • IL-10R1 antibody
    • IL-10RA antibody
    • IL10R antibody
    • IL10R1 antibody
    • IL10RA antibody
    • Interleukin 10 receptor alpha antibody
    • Interleukin 10 receptor alpha chain antibody
    • Interleukin-10 receptor subunit 1 antibody
    • Interleukin-10 receptor subunit alpha antibody
    see all

References

This product has been referenced in:
  • Wu X  et al. Morphological and functional changes of microglia cultured under different oxygen concentrations and the analysis of related mechanisms. Exp Ther Med 15:2015-2019 (2018). Read more (PubMed: 29434798) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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