Anti-IL-10RA antibody (ab228010)
Key features and details
- Rabbit polyclonal to IL-10RA
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-IL-10RA antibody
See all IL-10RA primary antibodies -
Description
Rabbit polyclonal to IL-10RA -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment within Human IL-10RA (internal sequence). The exact sequence is proprietary.
Database link: Q13651 -
Positive control
- WB: HepG2 whole cell lysate (ab7900). IHC-P: Human colon carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab228010 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 63 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 63 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
Receptor for IL10; binds IL10 with a high affinity. -
Tissue specificity
Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels. -
Involvement in disease
Inflammatory bowel disease 28 -
Sequence similarities
Belongs to the type II cytokine receptor family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3587 Human
- Omim: 146933 Human
- SwissProt: Q13651 Human
- Unigene: 504035 Human
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Alternative names
- CD210 antibody
- CDw210a antibody
- CDw210a antigen antibody
see all
Images
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Anti-IL-10RA antibody (ab228010) at 1/1000 dilution + HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate at 30 µg
Predicted band size: 63 kDa7.5% SDS-PAGE gel.
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Paraffin-embedded human colon carcinoma tissue stained for IL-10RA using ab228010 at 1/250 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab228010 has not yet been referenced specifically in any publications.