Key features and details
- Rabbit polyclonal to IL-10RA
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IL-10RA antibody
See all IL-10RA primary antibodies
DescriptionRabbit polyclonal to IL-10RA
Specificityab61775 detects endogenous levels of total IL-10RA protein.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide corresponding to Human IL-10RA (phospho Y496). (K-G-Y-L-K)
- HepG2 cell extracts treated with Na2VO3 (0.3nM, 40mins).
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab61775 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).|
FunctionReceptor for IL10; binds IL10 with a high affinity.
Tissue specificitySpleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
Involvement in diseaseInflammatory bowel disease 28
Sequence similaritiesBelongs to the type II cytokine receptor family.
- Information by UniProt
- CD210 antibody
- CDw210a antibody
- CDw210a antigen antibody
ab61775 has been referenced in 1 publication.
- García-Prieto E et al. Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10. PLoS One 5:e13242 (2010). WB ; Mouse . PubMed: 20949050