Recombinant Anti-IL-11 antibody [EPR15253] (ab187167)
![Western blot - Anti-IL-11 antibody [EPR15253] (ab187167)](https://www.abcam.com/ps/products/187/ab187167/Images/ab187167-220413-anti-il-11-antibody-epr15253-western-blot.jpg "Western blot - Anti-IL-11 antibody [EPR15253] (ab187167)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR15253] to IL-11
- Suitable for: WB
- Reacts with: Rat, Human, Recombinant fragment
Related conjugates and formulations
Overview
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Product name
Anti-IL-11 antibody [EPR15253]
See all IL-11 primary antibodies -
Description
Rabbit monoclonal [EPR15253] to IL-11 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat, Human, Recombinant fragment -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Active IL-11 full length recombinant protein; Rat plasma lysate.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR15253 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187167 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/1000 - 1/2000. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa).
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| Notes |
|---|
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WB
1/1000 - 1/2000. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa). |
Target
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Function
Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. -
Sequence similarities
Belongs to the IL-6 superfamily. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 3589 Human
- Entrez Gene: 171040 Rat
- Omim: 147681 Human
- SwissProt: P20809 Human
- SwissProt: Q99MF5 Rat
- Unigene: 467304 Human
- Unigene: 198483 Rat
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Alternative names
- Adipogenesis inhibitory factor antibody
- AGIF antibody
- IL 11 antibody
see all
Images
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Western blot - Anti-IL-11 antibody [EPR15253] (ab187167)Anti-IL-11 antibody [EPR15253] (ab187167) at 1/1000 dilution + Rat plasma lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 21 kDa -
![Western blot - Anti-IL-11 antibody [EPR15253] (ab187167)](https://www.abcam.com/ps/products/187/ab187167/Images/ab187167-220412-anti-il-11-antibody-epr15253-western-blot.jpg)
Western blot - Anti-IL-11 antibody [EPR15253] (ab187167)Anti-IL-11 antibody [EPR15253] (ab187167) at 1/2000 dilution + Recombinant human IL-11 protein (ab9553) at 0.01 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 21 kDa -
![Anti-IL-11 antibody [EPR15253] (ab187167)](https://www.abcam.com/ps/products/187/ab187167/Images/ab187167-3-benefits-of-recombinant-antibodies.png)
Anti-IL-11 antibody [EPR15253] (ab187167)
Datasheets and documents
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SDS download
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Datasheet download
Certificate of Compliance
References (3)
ab187167 has been referenced in 3 publications.
- Xu YL et al. Long non-coding RNA CASC7 is associated with the pathogenesis of heart failure via modulating the expression of miR-30c. J Cell Mol Med 24:11500-11511 (2020). PubMed: 32860492
- Tan HS et al. KRT8 upregulation promotes tumor metastasis and is predictive of a poor prognosis in clear cell renal cell carcinoma. Oncotarget 8:76189-76203 (2017). PubMed: 29100303
- Zheng H et al. TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling. Sci Rep 6:37070 (2016). WB ; Human . PubMed: 27901021