Anti-IL-12 antibody [1-1A4] (ab11446)
Key features and details
- Mouse monoclonal [1-1A4] to IL-12
- Suitable for: ELISA, IHC-Fr
- Reacts with: Human
- Isotype: IgG1
Overview
-
Product name
Anti-IL-12 antibody [1-1A4]
See all IL-12 primary antibodies -
Description
Mouse monoclonal [1-1A4] to IL-12 -
Host species
Mouse -
Specificity
ab11446 recognises the p40 subunit of human IL-12, and binds to both the free subunit and the p35/p40 heterodimer. This antibody reacts with both stimulated and unstimulated monocytes in immunohistology. -
Tested applications
Suitable for: ELISA, IHC-Frmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human IL-12.
-
General notes
This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
-
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
1-1A4 -
Myeloma
Sp2/0 -
Isotype
IgG1 -
Research areas
Associated products
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab11446 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ELISA | ||
IHC-Fr |
Notes |
---|
IHC-Fr: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
-
Function
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. -
Sequence similarities
Belongs to the IL-6 superfamily. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 3592 Human
- Entrez Gene: 3593 Human
- Omim: 161560 Human
- Omim: 161561 Human
- SwissProt: P29459 Human
- SwissProt: P29460 Human
- Unigene: 673 Human
-
Alternative names
- CLMF antibody
- CLMF p35 antibody
- CLMF p40 antibody
see all
Datasheets and documents
-
Datasheet download
References (0)
ab11446 has not yet been referenced specifically in any publications.