• Product name

  • Description

    Rabbit polyclonal to IL-12 p70
  • Host species

  • Tested applications

    Suitable for: Neutralising, WBmore details
  • Species reactivity

    Reacts with: Human, Monkey
  • Immunogen

    Recombinant full length protein corresponding to Human IL-12 p70.

  • General notes

    Endotoxin level: 115 pg/ml (LAL test).


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituents: PBS, 4.275% Trehalose
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    ab25105 was sequentially purified by ammonium sulphate precipitation and protein A affinity chromatography.
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab25105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Neutralising Use 8000µl for 105 cells.

8000 neutralizing units/mg of purified Rabbit IgG. One neutralizing unit is defined as the amount of IgG sufficient for a 50% inhibition of IFN gamma synthesis by human PBMC (2 x 105 cells) stimulated with 1 ng Human IL12. The optimal concentration should be determinded by the end user for each specific assay.

WB Use at an assay dependent concentration. Predicted molecular weight: 25 , 37 kDa.


  • Relevance

    IL-12 p70 is a disulfide bonded heterodimer of the IL-12 40 kDa and 35 kDa subunits.
  • Cellular localization

  • Database links

  • Alternative names

    • IL12A antibody
    • IL12B antibody
    • CLMF p35 antibody
    • CLMF p40 antibody
    • Cytotoxic lymphocyte maturation factor 35 kDa subunit antibody
    • Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody
    • Interleukin 12 alpha chain antibody
    • Interleukin-12 beta chain antibody
    • NK cell stimulatory factor chain 1 antibody
    • NK cell stimulatory factor chain 2 antibody
    • NKSF1 antibody
    • NKSF2 antibody
    see all


ab25105 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A


Thank you for contacting us again.

Your customer is absolutely right. I am sorry about this, but I made a mistake by confusing two different cases, both were for rat samples. Please accept my apology.

In this light, the homology is too low so that the antibody will probably not react with this species. As all of our IL12 p70 antibodies are raised against the recombinant full human protein, I am afraid none of our products is suitable.

I hope this information is still helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Use our products? Submit an Abreview. Earn rewards!

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Thank you very much for your interest in ab25105 Anti-IL12 p70 antibody.

To our knowledge, ab25105 has not been tested in rat. However, the homology between the human protein and the rat protein is very high with 99-100%. Therefore, I can offer a discount off a future purchase if you buy ab25105 now, test it in ratand submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of 1 free primary antibody.

Ifthey are interested in this offer, please follow these steps:

1. Reply to this e-mail to let me know that your customerwould like to proceed and test ab25105 in rat. We would need their email adress and the institution/companie they are working for.I will then send a discount code. This code must be issued before purchasing ab25105 so please wait for my reply before ordering.

2. Purchase ab25105either by phone, fax, or online.

3. Test it in rat.

4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews.

5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for anyprimary antibodyordered and the discount code is valid for 4 months after issue.

We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab25105turns out to be unsuitable for rat,you will still receive the discount on your next purchase after your Abreview has been submitted.

Please let me know if you have any questions about this offer and I would be happy to help you further.

The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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