Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-12A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Mouse IL-12A aa 30-80 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    PARCLSQSRNL LKTTDDMVKT AREKLKHYSC TAEDIDHEDI TRDQTSTLKT


    Database link: P43431

  • Positive control

    • Rat colitis tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 0.01% BSA, 50% Glycerol

    Aqueous buffered solution
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab203031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 24 kDa.
IHC-P 1/100 - 1/500.

When using a fluorescent probe the recommended dilution is 1/50 – 1/200

Target

  • Function

    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
  • Sequence similarities

    Belongs to the IL-6 superfamily.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • CLMF antibody
    • CLMF p35 antibody
    • Cytotoxic lymphocyte maturation factor 1 p35 antibody
    • Cytotoxic lymphocyte maturation factor 35 kDa subunit antibody
    • IL 12 subunit p35 antibody
    • IL 12A antibody
    • IL-12 subunit p35 antibody
    • IL-12A antibody
    • IL12A antibody
    • IL12A_HUMAN antibody
    • IL35 antibody
    • IL35 subunit antibody
    • Interleukin 12 alpha chain antibody
    • Interleukin 12 p35 antibody
    • Interleukin 12 subunit alpha antibody
    • Interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) antibody
    • Interleukin-12 subunit alpha antibody
    • Natural killer cell stimulatory factor 1 35 kD subunit antibody
    • NF cell stimulatory factor chain 1 antibody
    • NFSK antibody
    • NK cell stimulatory factor chain 1 antibody
    • NKSF1 antibody
    • P35 antibody
    see all

Images

  • Immunohistochemical analysis of Formalin-fixed, paraffin-embedded rat colitis labeling IL-12A with ab203031 at 1/200 dilution with DAB staining.

References

This product has been referenced in:

  • Ko BY  et al. Goblet cell loss abrogates ocular surface immune tolerance. JCI Insight 3:N/A (2018). Read more (PubMed: 29415888) »
  • Kamensek U  et al. Antitumor in situ vaccination effect of TNFa and IL-12 plasmid DNA electrotransfer in a murine melanoma model. Cancer Immunol Immunother 67:785-795 (2018). Read more (PubMed: 29468364) »
See all 4 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab203031.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up