Overview

  • Product name

    Anti-IL-13 antibody [A130D 12G5 1E4]
    See all IL-13 primary antibodies
  • Description

    Mouse monoclonal [A130D 12G5 1E4] to IL-13
  • Host species

    Mouse
  • Specificity

    Recognizes recombinant and native rat IL-13
  • Tested applications

    Suitable for: WB, ELISA, Flow Cyt, Dot blotmore details
  • Species reactivity

    Reacts with: Rat
  • Immunogen

    Recombinant full length protein corresponding to Rat IL-13.

  • Positive control

    • FACS: intracellular IL-13 can be detected in PMA/ionophore-stimulated rat splenocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab52538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 14 kDa.
ELISA Use at an assay dependent concentration.
Flow Cyt Use 0.1-1µg for 106 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Dot blot 1/500 - 1/1000.

Target

  • Function

    Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.
  • Involvement in disease

    Allergic rhinitis
  • Sequence similarities

    Belongs to the IL-4/IL-13 family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Allergic rhinitis antibody
    • ALRH antibody
    • BHR 1 antibody
    • BHR1 antibody
    • Bronchial hyperresponsiveness 1 (bronchial asthma) antibody
    • IL 13 antibody
    • IL-13 antibody
    • Il13 antibody
    • IL13_HUMAN antibody
    • Interleukin 13 antibody
    • Interleukin-13 antibody
    • interleukin13 antibody
    • MGC116786 antibody
    • MGC116788 antibody
    • MGC116789 antibody
    • NC 30 antibody
    • NC30 antibody
    • P 600 antibody
    • P600 antibody
    see all

References

ab52538 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab52538.
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