Anti-IL-15 antibody (ab166923)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-IL-15 antibody
See all IL-15 primary antibodies -
Description
Goat polyclonal to IL-15 -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee, Rhesus monkey
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Immunogen
Synthetic peptide corresponding to Human IL-15 aa 70-82 (internal sequence) (Cysteine residue). (NP_000576.1; NP_751915.1)
Sequence:DATLYTESDVHPS
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Positive control
- Human Bone Marrow lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab166923 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab166923 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 18 kDa. |
Target
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Function
Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. -
Tissue specificity
Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus. -
Sequence similarities
Belongs to the IL-15/IL-21 family. -
Cellular localization
Secreted and Cytoplasm. Nucleus. IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components. - Information by UniProt
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Database links
- Entrez Gene: 281248 Cow
- Entrez Gene: 100034058 Horse
- Entrez Gene: 3600 Human
- Entrez Gene: 397683 Pig
- Entrez Gene: 100009017 Rabbit
- Omim: 600554 Human
- SwissProt: Q28028 Cow
- SwissProt: P40933 Human
see all -
Alternative names
- IL 15 antibody
- IL-15 antibody
- IL15 antibody
see all
Images
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Western blot - Anti-IL-15 antibody (ab166923)Anti-IL-15 antibody (ab166923) at 1 µg/ml + Human Bone Marrow lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 18 kDa
Primary incubation was 1 hour
Protocols
Datasheets and documents
References
ab166923 has not yet been referenced specifically in any publications.
