Anti-IL-17A antibody (ab193955)

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Overview

  • Product name

    Anti-IL-17A antibody
    See all IL-17A primary antibodies

  • Description

    Rabbit polyclonal to IL-17A

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Human, Pig

  • Immunogen

    Recombinant full length protein corresponding to Cow IL-17A aa 22-153.
    Sequence:

    KAGVIIPQSP GCPPTEDKNF PQHVRVNLNI VNRSTNSRRP TDYHKRSTSP WTLHRNEDPE RYPSVIWEAK CSHSGCINAE GKVDHHMNSV TIQQEILVLR RESQHCPHSF RLEKMLVAVG CTCVTPIVRH LA


    Database link: Q687Y7

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • General notes

    Cross-reactivity determined in ELISA.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab193955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml.

Target

  • Function

    Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.

  • Tissue specificity

    Restricted to activated memory T-cells.

  • Sequence similarities

    Belongs to the IL-17 family.

  • Post-translational
    modifications

    Found both in glycosylated and nonglycosylated forms.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • CTLA 8 antibody
    • CTLA-8 antibody
    • CTLA8 antibody
    • cytotoxic T lymphocyte associated antigen 8 antibody
    • Cytotoxic T lymphocyte associated protein 8 antibody
    • Cytotoxic T lymphocyte associated serine esterase 8 antibody
    • Cytotoxic T-lymphocyte-associated antigen 8 antibody
    • IL 17 antibody
    • IL 17A antibody
    • IL-17 antibody
    • IL-17A antibody
    • IL17 antibody
    • IL17_HUMAN antibody
    • Il17a antibody
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    • interleukin 17A antibody
    • Interleukin-17A antibody
    • interleukin17 antibody
    • Interleukin17A antibody
    • OTTHUMP00000016597 antibody
    • OTTMUSP00000046003 antibody
    see all

References

Publishing research using ab193955? Please let us know so that we can cite the reference in this datasheet.

ab193955 has been referenced in 1 publication.

  • Fu Z  et al. Hesperidin protects against IL-1ß-induced inflammation in human osteoarthritis chondrocytes. Exp Ther Med 16:3721-3727 (2018). PubMed: 30233731

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