Anti-IL-17A antibody (ab193955)
Key features and details
- Rabbit polyclonal to IL-17A
- Reacts with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Human, Pig
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-IL-17A antibody
See all IL-17A primary antibodies -
Description
Rabbit polyclonal to IL-17A -
Host species
Rabbit -
Species reactivity
Reacts with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Human, Pig -
Immunogen
Recombinant full length protein corresponding to Cow IL-17A aa 1 to the C-terminus.
Database link: Q687Y7 -
General notes
Cross-reactivity determined in ELISA.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Target
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Function
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
Tissue specificity
Restricted to activated memory T-cells. -
Sequence similarities
Belongs to the IL-17 family. -
Post-translational
modificationsFound both in glycosylated and nonglycosylated forms. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 282863 Cow
- Entrez Gene: 3605 Human
- Entrez Gene: 16171 Mouse
- Entrez Gene: 449530 Pig
- Entrez Gene: 100339322 Rabbit
- Entrez Gene: 301289 Rat
- Omim: 603149 Human
- SwissProt: Q687Y7 Cow
see all -
Alternative names
- CTLA 8 antibody
- CTLA-8 antibody
- CTLA8 antibody
see all
Datasheets and documents
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Datasheet download
References (3)
ab193955 has been referenced in 3 publications.
- Cui C et al. Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR-145-3p/NFATc2/NF-?B axis. Int J Mol Med 48:N/A (2021). PubMed: 34036377
- Yang J et al. IL-1ß increases the expression of inflammatory factors in synovial fluid-derived fibroblast-like synoviocytes via activation of the NF-?B-mediated ERK-STAT1 signaling pathway. Mol Med Rep 20:4993-5001 (2019). PubMed: 31638264
- Fu Z et al. Hesperidin protects against IL-1ß-induced inflammation in human osteoarthritis chondrocytes. Exp Ther Med 16:3721-3727 (2018). PubMed: 30233731
