Anti-IL-17A antibody (ab214588)

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Overview

  • Product name

    Anti-IL-17A antibody
    See all IL-17A primary antibodies

  • Description

    Rabbit polyclonal to IL-17A

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse

  • Immunogen

    Synthetic peptide within Rat IL-17A aa 110-150 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    IQQEILVLKREPEKCPFTFRVEKMLVGVGCTCVSSIVRHAS


    Database link: Q61453

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Rat tongue and stomach tissues.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 1% BSA
  • Concentration information loading...

  • Purity

    Protein A purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab214588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/600. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.

  • Tissue specificity

    Restricted to activated memory T-cells.

  • Sequence similarities

    Belongs to the IL-17 family.

  • Post-translational
    modifications

    Found both in glycosylated and nonglycosylated forms.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • CTLA 8 antibody
      • CTLA-8 antibody
      • CTLA8 antibody
      • cytotoxic T lymphocyte associated antigen 8 antibody
      • Cytotoxic T lymphocyte associated protein 8 antibody
      • Cytotoxic T lymphocyte associated serine esterase 8 antibody
      • Cytotoxic T-lymphocyte-associated antigen 8 antibody
      • IL 17 antibody
      • IL 17A antibody
      • IL-17 antibody
      • IL-17A antibody
      • IL17 antibody
      • IL17_HUMAN antibody
      • Il17a antibody
      • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
      • interleukin 17A antibody
      • Interleukin-17A antibody
      • interleukin17 antibody
      • Interleukin17A antibody
      • OTTHUMP00000016597 antibody
      • OTTMUSP00000046003 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-17A antibody (ab214588)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-17A antibody (ab214588)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat tongue tissue labeling IL-17A with ab214588 at 1/600 dilution, followed by secondary antibody detection and DAB staining.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-17A antibody (ab214588)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-17A antibody (ab214588)

      Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat stomach tissue labeling IL-17A with ab214588 at 1/600 dilution, followed by secondary antibody detection and DAB staining.

    References

    ab214588 has not yet been referenced specifically in any publications.

    Publishing research using ab214588? Please let us know so that we can cite the reference in this datasheet.

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