Overview

  • Product name

    Anti-IL-17RA Receptor antibody [RM0104-10B27]
    See all IL-17RA Receptor primary antibodies
  • Description

    Rat monoclonal [RM0104-10B27] to IL-17RA Receptor
  • Host species

    Rat
  • Specificity

    This antibody detects mouse IL17A Receptor in Western blotting, but not IL17B Receptor.

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Recombinant fragment corresponding to Mouse IL-17RA Receptor (extracellular).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • Clonality

    Monoclonal
  • Clone number

    RM0104-10B27
  • Isotype

    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 96 kDa.

Target

  • Function

    Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
  • Tissue specificity

    Widely expressed.
  • Involvement in disease

    Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
  • Sequence similarities

    Contains 1 SEFIR domain.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CANDF5 antibody
    • CD217 antibody
    • CD217 antigen antibody
    • CDw217 antibody
    • CTLA8 antibody
    • HIL 17R antibody
    • hIL17R antibody
    • I17RA_HUMAN antibody
    • IL 17 receptor A antibody
    • IL 17 receptor antibody
    • IL 17RA antibody
    • IL-17 receptor A antibody
    • IL-17RA antibody
    • IL17 antibody
    • IL17A receptor antibody
    • IL17R antibody
    • IL17RA antibody
    • IMD51 antibody
    • Interleukin 17 receptor A antibody
    • Interleukin-17 receptor A antibody
    • MGC10262 antibody
    see all

References

This product has been referenced in:

  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB . Read more (PubMed: 27349908) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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