Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-17RB
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human IL-17RB (internal sequence). Gene Accssion: NP_061195.
    Database link: Q9NRM6

  • Positive control

    • Human thyroid cancer tissue and Human gastric cancer tissue.
  • General notes

     This product was previously labelled as IL-17B Receptor

     

Properties

Applications

Our Abpromise guarantee covers the use of ab198891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.

Target

  • Relevance

    Recently, a number of cytokines belonging to the interleukin IL-17 family have been identified. These are termed as IL-17B, IL-17C and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E have been independently isolated and have been designated as EV127 (in mouse) and IL-17RH1 (in human), respectively. IL-17E induces activation of NFkB pathway and like IL-17 also induces production of IL-8. IL-17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
  • Cellular localization

    Type I membrane protein (isoform 1). Secreted (isoform 2).
  • Database links

  • Alternative names

    • CRL 4 antibody
    • CRL4 antibody
    • Cytokine receptor CRL4 antibody
    • EVI 27 antibody
    • EVI27 antibody
    • IL 17 receptor B antibody
    • IL 17 receptor homolog 1 antibody
    • IL 17B receptor antibody
    • IL 17RB antibody
    • IL 17Rh1 antibody
    • IL17B Receptor antibody
    • IL17BR antibody
    • IL17RB antibody
    • IL17RH1 antibody
    • Interleukin 17 receptor B antibody
    • Interleukin 17 receptor homolog 1 antibody
    • Interleukin 17 receptor homolog antibody
    • Interleukin 17B receptor antibody
    • MGC5245 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue labeling IL17B Receptor with ab198891 at 1/40 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling IL17B Receptor with ab198891 at 1/40 dilution.

References

ab198891 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198891.
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