Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-17RB
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human IL-17RB. The exact sequence is proprietary.
    Database link: Q9NRM6

  • Positive control

    • WB: hIL17B Receptor transfected HEK-293T whole cell extracts; hIL17B Receptor transfected MCF-10A whole cell extracts.
  • General notes

     This product was previously labelled as IL-17B Receptor

     

Properties

Applications

Our Abpromise guarantee covers the use of ab229320 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.

Target

  • Relevance

    Recently, a number of cytokines belonging to the interleukin IL-17 family have been identified. These are termed as IL-17B, IL-17C and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E have been independently isolated and have been designated as EV127 (in mouse) and IL-17RH1 (in human), respectively. IL-17E induces activation of NFkB pathway and like IL-17 also induces production of IL-8. IL-17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
  • Cellular localization

    Type I membrane protein (isoform 1). Secreted (isoform 2).
  • Database links

  • Alternative names

    • CRL 4 antibody
    • CRL4 antibody
    • Cytokine receptor CRL4 antibody
    • EVI 27 antibody
    • EVI27 antibody
    • IL 17 receptor B antibody
    • IL 17 receptor homolog 1 antibody
    • IL 17B receptor antibody
    • IL 17RB antibody
    • IL 17Rh1 antibody
    • IL17B Receptor antibody
    • IL17BR antibody
    • IL17RB antibody
    • IL17RH1 antibody
    • Interleukin 17 receptor B antibody
    • Interleukin 17 receptor homolog 1 antibody
    • Interleukin 17 receptor homolog antibody
    • Interleukin 17B receptor antibody
    • MGC5245 antibody
    see all

Images

  • All lanes : Anti-IL-17RB antibody (ab229320) at 1/1000 dilution

    Lane 1 : Non-transfected HEK-293T whole cell extracts
    Lane 2 : hIL17B Receptor transfected HEK-293T whole cell extracts

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 56 kDa



    10% SDS-PAGE gel.

  • All lanes : Anti-IL-17RB antibody (ab229320) at 1/1000 dilution

    Lane 1 : MCF-10A whole cell extracts
    Lane 2 : hIL17B Receptor transfected MCF-10A whole cell extracts

    Lysates/proteins at 15 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 56 kDa

References

ab229320 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229320.
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