Anti-IL-18R Beta/IL-18RAP antibody (ab197832)
Key features and details
- Rabbit polyclonal to IL-18R Beta/IL-18RAP
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-IL-18R Beta/IL-18RAP antibody
See all IL-18R Beta/IL-18RAP primary antibodies -
Description
Rabbit polyclonal to IL-18R Beta/IL-18RAP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment corresponding to Human IL-18R Beta/IL-18RAP (internal sequence). Gene Accssion: BC106765.
Database link: O95256 -
Positive control
- RAW264.7 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab197832 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 68 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 68 kDa. |
Target
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Function
Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. -
Tissue specificity
Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. -
Sequence similarities
Belongs to the interleukin-1 receptor family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 16174 Mouse
- SwissProt: Q9Z2B1 Mouse
- Unigene: 20466 Mouse
- Unigene: 392521 Mouse
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Alternative names
- IL18RAP antibody
- Accessory protein like antibody
- Accessory protein-like antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab197832 has not yet been referenced specifically in any publications.