Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-18R1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human IL-18R1 aa 22-128.
    Sequence:

    CTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPR SSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFT ERQVTSK


    Database link: Q13478

  • Positive control

    • WB: Jurkat whole cell lysate. IHC-P: Human pancreas and lung tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.03% Proclin
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%
  • Clonality

    Polyclonal
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab235115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.
WB 1/500 - 1/5000. Predicted molecular weight: 62 kDa.

Target

  • Function

    Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
  • Tissue specificity

    Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines.
  • Sequence similarities

    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD218 antigen-like family member A antibody
    • CD218a antibody
    • CDw218a antibody
    • CDw218a antigen antibody
    • IL 1Rrp antibody
    • IL-18R-1 antibody
    • IL-18R1 antibody
    • IL-1Rrp antibody
    • IL1 receptor related protein antibody
    • IL1 receptor-related protein antibody
    • IL18R_HUMAN antibody
    • IL18R1 antibody
    • IL18RA antibody
    • Il18ralpha antibody
    • IL1R-rp antibody
    • IL1RRP antibody
    • Interleukin 18 receptor 1 antibody
    • Interleukin 18 receptor, alpha chain antibody
    • Interleukin-18 receptor 1 antibody
    see all

Images

  • Paraffin-embedded human lung tissue stained for IL18R1 using ab235115 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human pancreas tissue stained for IL18R1 using ab235115 at 1/100 dilution in immunohistochemical analysis.

  • Anti-IL-18R1 antibody (ab235115) at 1/500 dilution + Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate

    Secondary
    Goat polyclonal rabbit IgG at 1/50000 dilution

    Predicted band size: 62 kDa

References

ab235115 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab235115.
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