Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-1R-2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human IL-1R-2 aa 280-330 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    HIESAYPGGRV TEGPRQEYSE NNENYIEVPL IFDPVTREDL HMDFKCVVHN


    Database link: P27930

  • Positive control

    • Mouse lung lysates; Rat colon and Human kidney tissue.
  • General notes

    Previously labelled as IL1 Receptor II.

Properties

Applications

Our Abpromise guarantee covers the use of ab212208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

When using a fluorescent probe the recommended dilution is 1/50 – 1/200.

WB 1/100 - 1/1000. Predicted molecular weight: 45 kDa.

Target

  • Function

    Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1ra).
  • Sequence similarities

    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • IL1 Receptor II antibody
    • Antigen CDw121b antibody
    • CD121 antibody
    • CD121 antigen-like family member B antibody
    • CD121b antibody
    • CD121B Antigen antibody
    • CDw121b antibody
    • IL 1 type II receptor antibody
    • IL-1R-2 antibody
    • IL-1R-beta antibody
    • IL-1R2 antibody
    • IL-1RT-2 antibody
    • IL-1RT2 antibody
    • IL1R Beta antibody
    • Il1r-2 antibody
    • IL1R2 antibody
    • IL1R2_HUMAN antibody
    • IL1R2c antibody
    • IL1RB antibody
    • Interleukin 1 receptor type II variant 3 antibody
    • Interleukin 1 receptor, beta, type II antibody
    • Interleukin 1 receptor, type II antibody
    • Interleukin-1 receptor beta antibody
    • Interleukin-1 receptor type 2 antibody
    • Interleukin-1 receptor type II antibody
    • MGC137383 antibody
    • MGC47725 antibody
    • OTTHUMP00000207969 antibody
    • p68 antibody
    • Type II interleukin-1 receptor, beta antibody
    see all

Images

  • Anti-IL-1R-2 antibody (ab212208) at 1/300 dilution + Mouse lung lysates

    Secondary
    Goat anti-rabbit IgG (H+L), HRP at 1/5000 dilution

    Predicted band size: 45 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat colon tissue labeling IL-1R-2 with ab212208 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney labeling IL-1R-2 with ab212208 at 1/200 dilution overnight at 4°C followed by Goat anti-rabbit IgG (H+L), FITC conjugated at 1/500 dilution for 90 minutes. Nuclei are stained with DAPI. 

     

References

ab212208 has not yet been referenced specifically in any publications.

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