Overview

  • Product name

    Anti-IL-1RAPL1 antibody [MM0353-3R16]
    See all IL-1RAPL1 primary antibodies
  • Description

    Mouse monoclonal [MM0353-3R16] to IL-1RAPL1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human IL-1RAPL1.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • Clonality

    Monoclonal
  • Clone number

    MM0353-3R16
  • Isotype

    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab90453 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 80 kDa.

Target

  • Function

    May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK.
  • Tissue specificity

    Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver.
  • Involvement in disease

    Defects in IL1RAPL1 are the cause of mental retardation X-linked type 21 (MRX21) [MIM:300143]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • Sequence similarities

    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localization

    Cell membrane. Cytoplasm. May localize to the cell body and growth cones of dendrite-like processes.
  • Information by UniProt
  • Database links

  • Alternative names

    • IL 1 RAPL 1 antibody
    • IL 1RAPL 1 antibody
    • IL-1-RAPL-1 antibody
    • IL-1RAPL-1 antibody
    • IL1R8 antibody
    • IL1RAPL 1 antibody
    • IL1RAPL antibody
    • IL1RAPL-1 antibody
    • IL1RAPL1 antibody
    • Interleukin 1 receptor 8 antibody
    • Interleukin 1 receptor accessory protein like 1 antibody
    • Interleukin-1 receptor accessory protein-like 1 antibody
    • IRPL1_HUMAN antibody
    • Mental retardation X linked 10 antibody
    • Mental retardation X linked 21 antibody
    • Mental retardation X linked 34 antibody
    • MRX 21 antibody
    • MRX 34 antibody
    • MRX10 antibody
    • MRX21 antibody
    • MRX34 antibody
    • Oligophrenin 4 antibody
    • Oligophrenin-4 antibody
    • Oligophrenin4 antibody
    • OPHN 4 antibody
    • OPHN4 antibody
    • Three immunoglobulin domain containing IL 1 receptor related 2 antibody
    • Three immunoglobulin domain-containing IL-1 receptor-related 2 antibody
    • TIGIRR 2 antibody
    • TIGIRR-2 antibody
    • TIGIRR2 antibody
    • X linked interleukin 1 receptor accessory protein like 1 antibody
    • X-linked interleukin-1 receptor accessory protein-like 1 antibody
    see all

Images

  • Anti-IL-1RAPL1 antibody [MM0353-3R16] (ab90453) at 1/2000 dilution (Mouse anti human IL-1 R8) + Lysates of human placental tissue

    Predicted band size: 80 kDa
    Observed band size: 80 kDa

References

ab90453 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab90453.
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