Overview

  • Product name

    Anti-IL-2 antibody [AP-MAB0844]
    See all IL-2 primary antibodies
  • Description

    Rat monoclonal [AP-MAB0844] to IL-2
  • Host species

    Rat
  • Tested applications

    Suitable for: IP, IHC-Fr, Neutralising, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Recombinant full length protein corresponding to Mouse IL-2.

  • General notes


    Endotoxin Level: Extremely low level of LPS (< 0.002EU/µg IgG).


    ab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Properties

  • Form

    Lyophilised:Reconstitute with 1 ml sterile PBS.
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • Primary antibody notes

    ab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
  • Clonality

    Monoclonal
  • Clone number

    AP-MAB0844
  • Isotype

    IgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab80681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/400.
IHC-Fr 1/50.
Neutralising Use at an assay dependent concentration.

ab80681 can be used for neutralizing mouse IL2 in vitro.

Flow Cyt 1/100 - 1/200.

Target

  • Function

    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • Involvement in disease

    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • Sequence similarities

    Belongs to the IL-2 family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Aldesleukin antibody
    • IL 2 antibody
    • IL-2 antibody
    • IL2 antibody
    • IL2_HUMAN antibody
    • Interleukin 2 antibody
    • Interleukin-2 antibody
    • interleukin2 antibody
    • Involved in regulation of T cell clonal expansion antibody
    • Lymphokine antibody
    • OTTHUMP00000164090 antibody
    • POIL2 antibody
    • T Cell Growth Factor antibody
    • T-cell growth factor antibody
    • TCGF antibody
    see all

References

ab80681 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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