Key features and details
- Rat monoclonal [AP-MAB0844] to IL-2
- Suitable for: IP, IHC-Fr, Neutralising, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2
Product nameAnti-IL-2 antibody [AP-MAB0844]
See all IL-2 primary antibodies
DescriptionRat monoclonal [AP-MAB0844] to IL-2
Tested applicationsSuitable for: IP, IHC-Fr, Neutralising, Flow Cytmore details
Species reactivityReacts with: Mouse
Recombinant full length protein corresponding to Mouse IL-2.
Endotoxin Level: Extremely low level of LPS (< 0.002EU/µg IgG).
ab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
FormLyophilized:Reconstitute with 1 ml sterile PBS.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A purified
Purification notesThe IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
Primary antibody notesab80681 was produced by in vitro culture, from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
Our Abpromise guarantee covers the use of ab80681 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Neutralising||Use at an assay dependent concentration.
ab80681 can be used for neutralizing mouse IL2 in vitro.
|Flow Cyt||1/100 - 1/200.|
FunctionProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Involvement in diseaseNote=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
Sequence similaritiesBelongs to the IL-2 family.
- Information by UniProt
- Aldesleukin antibody
- IL 2 antibody
- IL-2 antibody
ab80681 has been referenced in 1 publication.
- Borghesi J et al. Canine amniotic membrane mesenchymal stromal/stem cells: Isolation, characterization and differentiation. Tissue Cell 58:99-106 (2019). PubMed: 31133253