Anti-IL-2 antibody [B-G5] (ab47194)

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Key features and details

  • Mouse monoclonal [B-G5] to IL-2
  • Reacts with: Human
  • Isotype: IgG1

Overview

  • Product name

    Anti-IL-2 antibody [B-G5]
    See all IL-2 primary antibodies

  • Description

    Mouse monoclonal [B-G5] to IL-2

  • Host species

    Mouse

  • Specificity

    This antibody is specific for both natural and recombinant IL2.

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Full length native protein (purified) corresponding to Human IL-2.
    Database link: P60568

  • Positive control

  • General notes

    Blocks IL2 induced proliferation on CTL-L2 murine cell line.

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Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.3
    Constituent: PBS
  • Concentration information loading...

  • Purity

    Ion Exchange Chromatography

  • Purification notes

    Sterile filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free.

  • Clonality

    Monoclonal

  • Clone number

    B-G5

  • Myeloma

    x63-Ag8.653

  • Isotype

    IgG1

  • Research areas

Target

  • Function

    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

  • Involvement in disease

    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

  • Sequence similarities

    Belongs to the IL-2 family.

  • Cellular localization

    Secreted.
  • Information by UniProt

  • Database links

    • Alternative names

      • Aldesleukin antibody
      • IL 2 antibody
      • IL-2 antibody
      • IL2 antibody
      • IL2_HUMAN antibody
      • Interleukin 2 antibody
      • Interleukin-2 antibody
      • interleukin2 antibody
      • Involved in regulation of T cell clonal expansion antibody
      • Lymphokine antibody
      • OTTHUMP00000164090 antibody
      • POIL2 antibody
      • T Cell Growth Factor antibody
      • T-cell growth factor antibody
      • TCGF antibody
      see all

    References (0)

    Publishing research using ab47194? Please let us know so that we can cite the reference in this datasheet.

    ab47194 has not yet been referenced specifically in any publications.

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