Anti-IL-2 Receptor alpha antibody [143-13] - BSA and Azide free (ab212488)

Overview

  • Product name

    Anti-IL-2 Receptor alpha antibody [143-13] - BSA and Azide free
    See all IL-2 Receptor alpha primary antibodies
  • Description

    Mouse monoclonal [143-13] to IL-2 Receptor alpha - BSA and Azide free
  • Host species

    Mouse
  • Specificity

    ab212488 recognizes epitope B, which is located at residue 3-104 of IL2 Receptor alpha and can effectively block IL-2 binding to IL2 Receptor alpha.
  • Tested applications

    Suitable for: Functional Studies, Flow Cyt, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human IL-2 Receptor alpha. (Stimulated Human leukocytes).

  • Positive control

    • PHA-stimulated human lymphocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab212488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.
Flow Cyt Use 0.5-1µg for 106 cells.

(in 0.1 ml).

ICC/IF Use a concentration of 0.5 - 1 µg/ml.

Target

  • Function

    Receptor for interleukin-2.
  • Involvement in disease

    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similarities

    Contains 2 Sushi (CCP/SCR) domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2 Receptor alpha antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

References

ab212488 has not yet been referenced specifically in any publications.

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