Key features and details
- Mouse monoclonal  to IL-2 Receptor alpha (Biotin)
- Suitable for: Flow Cyt, IHC-Fr
- Reacts with: Human
- Conjugation: Biotin
- Isotype: IgG1
Product nameAnti-IL-2 Receptor alpha antibody  (Biotin)
See all IL-2 Receptor alpha primary antibodies
DescriptionMouse monoclonal  to IL-2 Receptor alpha (Biotin)
Specificityab187683 stains less than 5% of resting human peripheral blood mononuclear cells in flow cytometry.
Tested applicationsSuitable for: Flow Cyt, IHC-Frmore details
Species reactivityReacts with: Human
Tissue, cells or virus corresponding to Human IL-2 Receptor alpha. Stimulated human leukocytes
Database link: P01589
Epitopeab187683 recognizes epitope region C of the IL-2 receptor complex.
- Human tonsil
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark.
Storage bufferpH: 7.20
Preservative: 0.05% KATHON™ CG/ICP
Constituents: 99% PBS, 0.5% BSA
Concentration information loading...
PurityProtein G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab187683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|IHC-Fr||Use a concentration of 10 µg/ml.|
FunctionReceptor for interleukin-2.
Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
- Information by UniProt
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
ab187683 has not yet been referenced specifically in any publications.