Anti-IL-2 Receptor alpha antibody [BC96] (Phycoerythrin) (ab134476)

Overview

  • Product name

    Anti-IL-2 Receptor alpha antibody [BC96] (Phycoerythrin)
    See all IL-2 Receptor alpha primary antibodies
  • Description

    Mouse monoclonal [BC96] to IL-2 Receptor alpha (Phycoerythrin)
  • Host species

    Mouse
  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human, Chimpanzee, Baboon, Cynomolgus monkey, Rhesus monkey
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • PHA-stimulated normal Human peripheral blood cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab134476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    Receptor for interleukin-2.
  • Involvement in disease

    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similarities

    Contains 2 Sushi (CCP/SCR) domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2 Receptor alpha antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Images

  • Flow Cytometry analysis of human peripheral blood lymphocytes labeling IL-2 Receptor alpha with ab134476 at 5 µL (0.06 µg) (right panel) or 0.06 µg Mouse IgG1 (Phycoerythrin)  isotype control (left panel).

References

ab134476 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Flow Cytometry
Sample
Human Cell (PBMC)
Permeabilization
No
Gating Strategy
lymphocytes
Specification
PBMC
Preparation
Cell harvesting/tissue preparation method: Ficoll-hypaque gradrient
Sample buffer: PBS

Abcam user community

Verified customer

Submitted Feb 19 2013

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