Anti-IL-2 Receptor alpha antibody [MEM-181], prediluted (PerCP/Cy5.5®) (ab157308)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-IL-2 Receptor alpha antibody [MEM-181], prediluted (PerCP/Cy5.5®)
See all IL-2 Receptor alpha primary antibodies -
DescriptionMouse monoclonal [MEM-181] to IL-2 Receptor alpha, prediluted (PerCP/Cy5.5®)
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Host speciesMouse
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ConjugationPerCP/Cy5.5®. Ex: 482nm, Em: 690nm
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Tested applicationsSuitable for: Flow Cytmore details
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Species reactivityReacts with: Human
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Immunogen
Tissue, cells or virus corresponding to Human IL-2 Receptor alpha.
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General notes
Purified antibody is conjugated with tandem dye PerCP/Cy5.5® under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C.
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Storage bufferPreservative: 0.1% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading... -
PuritySize exclusion
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ClonalityMonoclonal
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Clone numberMEM-181
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IsotypeIgG1
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Research areas
Associated products
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Alternative Versions
- Anti-IL-2 Receptor alpha antibody [MEM-181] (PerCP) (ab130737)
- Anti-IL-2 Receptor alpha antibody [MEM-181] (FITC) (ab18275)
- Anti-IL-2 Receptor alpha antibody [MEM-181] (PE/Cy7 ®) (ab234252)
- Anti-IL-2 Receptor alpha antibody [MEM-181] (Phycoerythrin) (ab36419)
- Anti-IL-2 Receptor alpha antibody [MEM-181] (ab8235)
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab157308 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
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| Flow Cyt | Use 4µl for 106 cells. (or 100 µl of whole blood).
ab157226 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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Target
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FunctionReceptor for interleukin-2.
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Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
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Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
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Cellular localizationMembrane.
- Information by UniProt
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Database links
- Entrez Gene: 3559 Human
- Omim: 147730 Human
- SwissProt: P01589 Human
- Unigene: 231367 Human
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Alternative names
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
see all
Protocols
References
This product has been referenced in:
- Drbal K et al. Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. Int Immunol 19:675-84 (2007). Read more (PubMed: 17446208) »
