Anti-IL-2 Receptor alpha antibody [MRC OX-39] (Biotin) (ab33836)


  • Product name
    Anti-IL-2 Receptor alpha antibody [MRC OX-39] (Biotin)
    See all IL-2 Receptor alpha primary antibodies
  • Description
    Mouse monoclonal [MRC OX-39] to IL-2 Receptor alpha (Biotin)
  • Host species
  • Conjugation
  • Specificity
    ab33836 recognizes IL-2 receptor alpha (55kDa) expressed by activated T cells, but not resting lymphocytes, and by dendritic cells found in the thymus medulla.
  • Tested applications
    Suitable for: Flow Cyt, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Tissue, cells or virus corresponding to Rat IL-2 Receptor alpha.

  • General notes


    This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate lysine paraformaldehyde). Clone OX 39 has been shown to weakly inhibit the binding of IL-2 to Con A stimulated spleen blasts.


  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab33836 was purified from tissue culture supernatant.
  • Primary antibody notes
    This clone has been described reacting with paraffin-embedded material following PLP fixation (periodate lysine paraformaldehyde). Clone OX 39 has been shown to weakly inhibit the binding of IL2 to Con A stimulated spleen blasts.
  • Clonality
  • Clone number
    MRC OX-39
  • Myeloma
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab33836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10.

use 10µl of the suggested working dilution to label 106 cells.




ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


IHC-P Use at an assay dependent concentration.


  • Function
    Receptor for interleukin-2.
  • Involvement in disease
    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similarities
    Contains 2 Sushi (CCP/SCR) domains.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2 Receptor alpha antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all


This product has been referenced in:
  • Whiteland JL  et al. Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies. J Histochem Cytochem 43:313-20 (1995). Read more (PubMed: 7868861) »
  • Paterson DJ  et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 24:1281-90 (1987). Read more (PubMed: 2828930) »
See all 2 Publications for this product

Customer reviews and Q&As


Thank you for contacting us. Please find below the list of the Abcam IL2 receptor alpha antibodies which have been tested in Rat (IL2 receptor alpha antibodies are also known as CD25 antibodies : ab33854 unconjugated Mouse monoclonal ab33848 PE conjugated Mouse mono ab33836 biotin conjugated Mouse mono ab95547 allophycocyanin conjugated Mouse mono ab33853 FITC conjugated Mouse mono I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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