Overview

  • Product name

    Anti-IL-2 Receptor alpha antibody [P4A10]
    See all IL-2 Receptor alpha primary antibodies
  • Description

    Mouse monoclonal [P4A10] to IL-2 Receptor alpha
  • Host species

    Mouse
  • Tested applications

    Suitable for: Flow Cyt, WBmore details
  • Species reactivity

    Reacts with: Dog
  • Immunogen

    Tissue, cells or virus corresponding to Dog IL-2 Receptor alpha. Enriched and stimulated Canine T cells.
    Database link: O62802

  • Positive control

    • Canine peripheral blood lymphocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab195001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/50 - 1/100.

Use 10µl of the suggested working dilution to label 1x106 cells in 100µl.

 

 

 

 

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.

ab195001 produces a double band at approximately 55kDa under non-reducing conditions. A non-specific band may be observed at 116kDa

Target

  • Function

    Receptor for interleukin-2.
  • Involvement in disease

    Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
  • Sequence similarities

    Contains 2 Sushi (CCP/SCR) domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Interleukin 2 receptor alpha chain antibody
    • CD25 antibody
    • CD25 antigen antibody
    • IDDM10 antibody
    • IL 2 receptor alpha subunit antibody
    • IL-2 receptor subunit alpha antibody
    • IL-2-RA antibody
    • IL-2R subunit alpha antibody
    • IL2 RA antibody
    • IL2 Receptor alpha antibody
    • IL2-RA antibody
    • IL2R antibody
    • IL2R, alpha chain antibody
    • IL2RA antibody
    • IL2RA_HUMAN antibody
    • IMD41 antibody
    • Interleukin 2 receptor alpha antibody
    • Interleukin 2 receptor antibody
    • Interleukin-2 receptor subunit alpha antibody
    • p55 antibody
    • t-cell growth factor receptor antibody
    • TAC antibody
    • TAC antigen antibody
    • TCGFR antibody
    see all

Images

  • Flow cytometric analysis of Canine peripheral blood lymphocytes labeling IL-2 Receptor alpha with ab195001 at 1/50 dilution followed by Goat anti-mouse IgG FITC secondary antibody and counterstained with Rat anti-Dog CD4 Alexa Fluor antibody.

References

ab195001 has not yet been referenced specifically in any publications.

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