Key features and details
- Rat monoclonal [PC61.5] to IL-2 Receptor alpha (PE)
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Product nameAnti-IL-2 Receptor alpha antibody [PC61.5] (PE)
See all IL-2 Receptor alpha primary antibodies
DescriptionRat monoclonal [PC61.5] to IL-2 Receptor alpha (PE)
ConjugationPE. Ex: 488nm, Em: 575nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
- C57Bl/6 mouse spleen cells
ab210334 is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used for depletion of Treg cells in vivo, as well as to distinguish Treg cells from naive or conventional T cells which are CD25-.
The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
Concentration information loading...
Purification notesab210334 was purified from tissue culture supernatant.
Light chain typelambda
- Anti-IL-2 Receptor alpha antibody [PC61.5] (APC) (ab210330)
- Anti-IL-2 Receptor alpha antibody [PC61.5] (FITC) (ab210332)
- Anti-IL-2 Receptor alpha antibody [PC61.5] - Low endotoxin, Azide free (ab210333)
- Anti-IL-2 Receptor alpha antibody [PC61.5] (PE/Cy7®) (ab210335)
- Anti-IL-2 Receptor alpha antibody [PC61.5] (PerCP/Cy5.5®) (ab210336)
Our Abpromise guarantee covers the use of ab210334 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
Use at 0.125 µg.
FunctionReceptor for interleukin-2.
Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Sequence similaritiesContains 2 Sushi (CCP/SCR) domains.
- Information by UniProt
- Interleukin 2 receptor alpha chain antibody
- CD25 antibody
- CD25 antigen antibody
ab210334 has not yet been referenced specifically in any publications.