Key features and details
- Rabbit polyclonal to IL-20R1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-IL-20R1 antibody
See all IL-20R1 primary antibodies
DescriptionRabbit polyclonal to IL-20R1
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
- Human endometrial cancer and rat tongue tissues; rat brain and mouse liver tissue lysates.
Protein previously labeled as IL20 Receptor alpha.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 0.01% BSA, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203196 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use at 1/50 - 1/200 with fluorescent detection methods.
|WB||1/100 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 62 kDa).|
FunctionThe IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Tissue specificityWidely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
Sequence similaritiesBelongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.
- Information by UniProt
- class II cytokine receptor ZCYTOR7 antibody
- CRF2 8 antibody
- CRF2-8 antibody
Immunohistochemical analysis of formalin-fixed paraffin-embedded human endometrial cancer tissue labeling IL-20R1 with ab203196 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed paraffin-embedded rat tongue tissue labeling IL-20R1 with ab203196 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
All lanes : Anti-IL-20R1 antibody (ab203196) at 1/200 dilution
Lane 1 : Rat kidney tissue lysate
Lane 2 : Rat brain tissue lysate
All lanes : Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/3000 dilution
Predicted band size: 62 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
Anti-IL-20R1 antibody (ab203196) at 1/300 dilution + mouse liver tissue lysate
Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/5000 dilution
Predicted band size: 62 kDa
ab203196 has been referenced in 3 publications.
- Lu SW et al. IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models. Nat Commun 11:4611 (2020). PubMed: 32929072
- Weng YH et al. Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation. Front Immunol 10:968 (2019). PubMed: 31114590
- An W et al. Exogenous IL-19 attenuates acute ischaemic injury and improves survival in male mice with myocardial infarction. Br J Pharmacol N/A:N/A (2018). PubMed: 30460984