Anti-IL-20R2 antibody [20RNTC] (ab95824)

Submit a review Submit a question References (3)
Immunocytochemistry/ Immunofluorescence - Anti-IL-20R2 antibody [20RNTC] (ab95824)
  • Flow Cytometry - Anti-IL-20R2 antibody [20RNTC] (ab95824)

Key features and details

  • Rat monoclonal [20RNTC] to IL-20R2
  • Suitable for: Flow Cyt, ICC/IF
  • Reacts with: Mouse, Human
  • Isotype: IgG2a

Overview

  • Product name

    Anti-IL-20R2 antibody [20RNTC]
    See all IL-20R2 primary antibodies

  • Description

    Rat monoclonal [20RNTC] to IL-20R2

  • Host species

    Rat

  • Specificity

    ab95824 recognizes Mouse and Human IL-20R2 in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1

  • Tested applications

    Suitable for: Flow Cyt, ICC/IFmore details

  • Species reactivity

    Reacts with: Mouse, Human

  • Immunogen

    Recombinant fragment corresponding to Mouse IL-20R2 (extracellular).

  • Positive control

    • Fixed and permeabilized A375 cells

  • General notes

    Protein previously labeled as IL20RB.

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituent: 1% PBS
  • Concentration information loading...

  • Purity

    Protein G purified

  • Clonality

    Monoclonal

  • Clone number

    20RNTC

  • Isotype

    IgG2a

  • Light chain type

    kappa

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 1 - 10 µg/ml.

ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

 
ICC/IF Use a concentration of 1 - 10 µg/ml.

Target

  • Function

    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

  • Tissue specificity

    Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.

  • Sequence similarities

    Belongs to the type II cytokine receptor family.
    Contains 2 fibronectin type-III domains.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • DIRS1 antibody
      • Fibronectin type III domain containing 6 antibody
      • FNDC6 antibody
      • I20RB_HUMAN antibody
      • IL 20R beta antibody
      • IL 20R2 antibody
      • IL-20 receptor subunit beta antibody
      • IL-20R-beta antibody
      • IL-20R2 antibody
      • IL-20RB antibody
      • IL20RB antibody
      • Interleukin 20 receptor beta antibody
      • Interleukin 20 receptor beta chain precursor antibody
      • Interleukin 20 receptor II antibody
      • Interleukin-20 receptor subunit beta antibody
      • MGC34923 antibody
      see all

    Images

    • Immunocytochemistry/ Immunofluorescence - Anti-IL-20R2 antibody [20RNTC] (ab95824)
      Immunocytochemistry/ Immunofluorescence - Anti-IL-20R2 antibody [20RNTC] (ab95824)
      Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 µg/ml of ab95824 (right) or Rat IgG2a ? Isotype Control Purified (left) followed by Anti-Rat IgG Biotin and then Streptavidin FITC.
    • Flow Cytometry - Anti-IL-20R2 antibody [20RNTC] (ab95824)
      Flow Cytometry - Anti-IL-20R2 antibody [20RNTC] (ab95824)

      Mouse IL-20R2-GFP 293 transfectants stained with 0.25ug ab95824 + anti-rat IgG PE

    References (3)

    Publishing research using ab95824? Please let us know so that we can cite the reference in this datasheet.

    ab95824 has been referenced in 3 publications.

    • Weng YH  et al. Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation. Front Immunol 10:968 (2019). PubMed: 31114590
    • He B  et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . PubMed: 23441190
    • Hsing CH  et al. Upregulated IL-19 in breast cancer promotes tumor progression and affects clinical outcome. Clin Cancer Res 18:713-25 (2012). ICC/IF . PubMed: 22186257

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab95824.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com