Anti-IL-20R2 antibody [20RNTC] (ab95824)
- Datasheet
- References (3)
- Protocols
Overview
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Product name
Anti-IL-20R2 antibody [20RNTC]
See all IL-20R2 primary antibodies -
Description
Rat monoclonal [20RNTC] to IL-20R2 -
Host species
Rat -
Specificity
ab95824 recognizes Mouse and Human IL-20R2 in either of its two heterodimeric complexes formed by pairing with IL-20RA or IL-22RA1 -
Tested applications
Suitable for: Flow Cyt, ICC/IF, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment corresponding to Mouse IL-20R2 (extracellular).
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Positive control
- Fixed and permeabilized A375 cells
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General notes
Protein previously labeled as IL20RB.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 1% PBS, pH 7.2 -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
20RNTC -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab95824 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use a concentration of 1 - 10 µg/ml. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
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| ICC/IF | Use a concentration of 1 - 10 µg/ml. | |
| WB | Use at an assay dependent concentration. PubMed: 23441190 |
Target
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Function
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24. -
Tissue specificity
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin. -
Sequence similarities
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 53833 Human
- Entrez Gene: 213208 Mouse
- Omim: 605621 Human
- SwissProt: Q6UXL0 Human
- Unigene: 61232 Human
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Alternative names
- DIRS1 antibody
- Fibronectin type III domain containing 6 antibody
- FNDC6 antibody
see all
Images
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![Immunocytochemistry/ Immunofluorescence - Anti-IL-20R2 antibody [20RNTC] (ab95824)](https://www.abcam.com/ps/products/95/ab95824/Images/ab95824-110070-anti-il-20r2-antibody-20rntc-immunofluorescence.jpg)
Immunocytochemistry/ Immunofluorescence - Anti-IL-20R2 antibody [20RNTC] (ab95824)Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 µg/ml of ab95824 (right) or Rat IgG2a ? Isotype Control Purified (left) followed by Anti-Rat IgG Biotin and then Streptavidin FITC. -
![Flow Cytometry - Anti-IL-20R2 antibody [20RNTC] (ab95824)](https://www.abcam.com/ps/products/95/ab95824/Images/ab95824-110069-anti-il-20r2-antibody-20rntc-flow-cytometry.jpg)
Flow Cytometry - Anti-IL-20R2 antibody [20RNTC] (ab95824)Mouse IL-20R2-GFP 293 transfectants stained with 0.25ug ab95824 + anti-rat IgG PE
Protocols
Datasheets and documents
References
This product has been referenced in:
- Weng YH et al. Blocking IL-19 Signaling Ameliorates Allergen-Induced Airway Inflammation. Front Immunol 10:968 (2019). Read more (PubMed: 31114590) »
- He B et al. A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy. PLoS One 8:e56414 (2013). WB ; Mouse . Read more (PubMed: 23441190) »
