Product nameAnti-IL-21R antibody
See all IL-21R primary antibodies
DescriptionRabbit polyclonal to IL-21R
Tested applicationsSuitable for: ELISA, Flow Cyt, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
- Mouse thymus/spleen.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab13268 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
FunctionThis is a receptor for interleukin-21.
Tissue specificitySelectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 2 fibronectin type-III domains.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
modificationsC-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.
- Information by UniProt
- CD360 antibody
- IL 21R antibody
- IL-21 receptor antibody
This product has been referenced in:
- Qiu F et al. A genome-wide association study identifies six novel risk loci for primary biliary cholangitis. Nat Commun 8:14828 (2017). IHC-P ; Human . Read more (PubMed: 28425483) »
- Tzartos JS et al. IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain. Am J Pathol 178:794-802 (2011). IHC-P ; Human . Read more (PubMed: 21281812) »