Anti-IL-22 antibody (ab181007)
Key features and details
- Rabbit polyclonal to IL-22
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-IL-22 antibody
See all IL-22 primary antibodies -
Description
Rabbit polyclonal to IL-22 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human IL-22 (internal sequence). Peptide corresponds to 17 amino acids near the center.
Database link: NP_065386 -
Positive control
- HeLa whole cell lysate (ab150035).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab181007 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 20 kDa.
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 20 kDa. |
Target
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Function
Cytokine that contributes to the inflammatory response in vivo. -
Sequence similarities
Belongs to the IL-10 family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 50616 Human
- Omim: 605330 Human
- SwissProt: Q9GZX6 Human
- Unigene: 287369 Human
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Alternative names
- Cytokine Zcyto18 antibody
- IL 10 related T cell derived inducible factor antibody
- IL 21 antibody
see all
Images
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All lanes : Anti-IL-22 antibody (ab181007) at 1 µg
Lane 1 : HeLa cell lysate with absent
Lane 2 : HeLa cell lysate with present
Lysates/proteins at 15 µg per lane.
Predicted band size: 20 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (3)
ab181007 has been referenced in 3 publications.
- Gu P et al. Protective function of interleukin-22 in pulmonary fibrosis. Clin Transl Med 11:e509 (2021). PubMed: 34459137
- Li Z et al. Interleukin-22 modulates cisplatin sensitivity of osteosarcoma cells by regulating the STAT3 signaling pathway. Exp Ther Med 19:1379-1387 (2020). PubMed: 32010312
- Wang L et al. Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways. Sci Rep 7:12044 (2017). PubMed: 28935920